Clinical Genomics Laboratory

Whole genome sequencing provides comprehensive analysis of the entire DNA sequence of an organism. This service enables detection of all classes of genetic variation, including single nucleotide changes, structural variants, and complex rearrangements making it a powerful tool for rare disease research, population genomics, and precision medicine studies. Sidra Medicine’s genomics infrastructure delivers high-coverage, high-quality sequencing with rapid turnaround to support both research and clinical applications.

Sidra Medicine offers integrated multiomics services that combine high-throughput genomic and transcriptomic sequencing with complementary imaging and flow cytometry. This integrated approach enables comprehensive molecular and cellular characterization, linking genetic and transcriptional profiles with phenotypic, spatial, and cellular context. The workflows support a wide range of assays and are designed to accommodate diverse study designs and sample types. By integrating sequencing data with imaging and flow cytometry outputs, this service provides multidimensional insights to support functional genomics, translational research, and precision medicine initiatives.

Sidra Medicine offers single-cell sequencing services using microfluidics-based partitioning technology to enable high-resolution analysis of cellular heterogeneity. This platform supports single-cell RNA sequencing, immune repertoire profiling, and feature barcoding, allowing simultaneous interrogation of gene expression and cell identity across thousands of individual cells per sample. Single-cell sequencing provides powerful insights into cell-type composition, developmental trajectories, and disease-associated cellular states, supporting advanced applications in immunology, cancer research, developmental biology, and translational studies

We provide standardized and validated library preparation workflows to support a wide range of sequencing applications. Our processes are optimized for different sample types and study requirements, ensuring consistency, data quality, and reproducibility across genomic projects.

Targeted and custom sequencing approaches are available to support focused genomic investigations, including specific genes, regions, or pathways of interest. These approaches offer a cost-effective and efficient alternative to broader sequencing strategies for hypothesis-driven and translational research studies.