Omics Core

Our Biorepository provides a centralized, modern infrastructure for the standardized processing, tracking and long-term storage of research and clinical biospecimens. The facility supports a wide range of controlled storage conditions, including ambient, refrigerated, frozen, ultra-low temperature, and cryogenic environments, according to specimen-specific requirements, Comprehensive sample tracking, barcoded inventory systems, and documented chain-of-custody ensure traceability, while continuous environmental monitoring and validated backup systems safeguard specimen integrity and compliance with international biobanking and quality standards.

We provide high quality DNA and RNA isolation services tailored to a wide range of sample types and downstream applications. Both automated and manual workflows are available, enabling flexibility in processing diverse biological sources while ensuring consistency, scalability, and optimal yield. The isolation of High Molecular Weight (HMW) DNA is also supported to meet the requirements of downstream long-read sequencing applications.

Sidra Medicine offers advanced long-read sequencing services using the leading platforms available on the market, enabling sequencing of substantially longer DNA fragments compared to conventional short-read methods. Long-read sequencing provides enhanced resolution of complex genomic regions, structural variants, repeat expansions, and haplotype structures, and support high-quality de novo genome assembly, delivering deeper insights into genomic architecture that are essential for rare disease research and novel discovery. Our facility is a PacBio Certified Service Provider, reflecting adherence to rigorous quality standards and expert execution.

Sidra Medicine provides Illumina array–based services for genome-wide DNA methylation profiling and genotyping, enabling high-throughput, cost-effective interrogation of genetic and epigenetic variation. These arrays support comprehensive analysis of single nucleotide polymorphisms (SNPs), copy number variation, and DNA methylation patterns across the genome, with particular strength in pharmacogenomics applications. Genotyping arrays facilitate the identification of clinically relevant variants associated with drug metabolism, efficacy, and toxicity, while methylation arrays enable epigenome-wide association studies and regulatory landscape analysis. This platform delivers robust, reproducible data suitable for population studies, translational research, and clinically oriented investigations.

Our Sanger Sequencing service provides highly accurate, gold-standard DNA sequence validation for specific genomic regions. Ideal for confirming variants identified by high-throughput methods, checking targeted mutation sites, or small-scale sequencing projects. This service supports research validation needs with dependable, precise results.

Sidra Medicine provides high-throughput quantitative PCR (qPCR) services for genotyping (GT) and gene expression (GE) analyses, enabling rapid, sensitive, and scalable nucleic acid quantification. The provision of this service supports large-scale sample processing with high reproducibility and precision, making it well suited for variant validation, allele discrimination, expression profiling, and biomarker studies. Flexible assay formats and multiplexing capabilities allow customization based on project scope and downstream requirements, supporting applications across population studies, translational research, and clinically oriented investigations.