Annalisa Terranegra, PhD

Principal Investigator – Assistant Level
Laboratory of Nutritional Genomics and Metabolism

Email: aterranegra (@) sidra.org
Phone: +974 40037396
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  • Biography

    Annalisa obtained her MSc degree in Biological Sciences cum laudae in 2000 at the University of Siena, Italy, PhD in Molecular Medicine in 2007 at the University of Milan, Italy and Post-graduate Diploma cum laudae in Nutritional Sciences at the University of Milan, Italy in 2015.

    Before to join Sidra Medicine in 2014, Annalisa achieved strong experience in molecular biology and genetics during her career at the University of Milan, Italy, as a post-graduation fellow (2001-2003), PhD fellow (2003-2006) and Post-Doc position (2007-2010). Annalisa covered a consultant position in genetics at San Raffaele Hospital, Milan, Italy (2010-2012) and a research fellow position in nutrition at San Paolo Hospital, Milan, Italy (2013-2014).

    Annalisa also has extensive teaching experience as Assistant Professor in Nephrology (2007-2010) and in Dietetic Sciences and Technologies (2010-2013) at University of Milan, Italy; Lecturer in Molecular Medicine PhD course (2009-2011) at University of Milan. Annalisa currently cover the position of adjunct Associate Professor, since 2015, in the College of Science and Engineering at Hamad bin Khalifa University, Qatar and of adjunct Assistant Professor, since 2018, in the College of Health Sciences at Qatar University, Qatar.
  • Our Research and Approach

    Laboratory of Nutritional Genomics and Metabolism (NutriGen Lab) is interested to characterize the mechanisms underlying the role of food and nutrients in the development and the management of non-communicable diseases, such as diabetes, obesity, cardiovascular diseases, cancer, etc. NutriGen lab research studies are focused on understanding the effect of diet on gut microbiota and epigenetic mechanisms, as well as diet interaction with the genomic background, using the most advanced technologies such as bacterial 16S rRNA-sequencing, DNA-methylation arrays, DNA genotyping and nutritional assessment (BMI, body fat mass composition, diet and lifestyle habits records, nutrition and micronutrient computing). Thanks to local and international collaborations, NutriGen lab is currently running many studies on diabetes, obesity, cardiovascular diseases, inflammatory bowel diseases, and perturbation of the mother-baby axis during the pregnancy and early baby life.
  • Lab Members

    Dhinoth Kumar Bangarusamy, PhD
    Staff Scientist
    Email: dbangarusamy (@) sidra.org

    Arun Prasath Lakshmanan, PhD
    Postdoctoral Fellow
    Email: alakshmanan (@) sidra.org

    Sara Zaidan, Bsc
    Research Specialist
    Email: szaidan (@) sidra.org

    Shaikha Al Abduljabbar, Bsc
    Research Specialist
    Email: salabduljabbar (@) sidra.org

SELECTED PUBLICATIONS(equal contribution, *corresponding):

  • Mattei V, Murugesan S, Al Hashmi M, Mathew R, James N, Singh P, Kumar M, Lakshmanan AP, Terranegra A, Al Khodor S and Tomei S. Evaluation of Methods for the extraction of Microbial DNA From Vaginal Swabs Used for Microbiome Studies. Front Cell Infect Microbiol (2019) 9:197.
  • Brummaier T, Syed Ahamed Kabeer B, Lindow S, Konje JC, Pukrittayaamee S, Utzinger J, Toufiq M, Antoniou A, Marr AK, Suriyakan S, Kino T, Al Khodor S, Terranegra A, Nosten F, Paris DH, McGready R, Chaussabel D. A prospective cohort for the investigation of alteration in temporal transcriptional and microbiome trajectories preceding preterm birth: a study protocol. BMJ Open (2018) 9:e023417.
  • Terranegra A*. Future Perspectives in Nutritional Genomics to Investigate Non-Communicable Diseases in Pregnant Women and the Offspring in Qatar. Updates in Nutritional Disorders and Therapy (2016) 1:1-3.
  • Soldati L, Tomei S, Wang E, Kerkadi A, El-Obeid T, Amuna P, Chouchane L, and Terranegra A*. Potential Nutrigenomic Approaches to Reduce the High Incidence of Obesity in Qatar. J Nutr Food Sci(2016) 6:472.
  • RizziF, ContiC, Dogliotti E, Terranegra A, Salvi E, Braga D, Ricca F, Lupoli S, Mingione A, Pivari F, Brasacchio C, Barcella M, Chittani M, D’Avila F, Turiel M, Lazzaroni M, Soldati L, Daniele Cusi D and Barlassina C. Interaction between polyphenols intake and PON1 gene variants on markers of cardiovascular disease: a nutrigenetic observational study. J Transl Med (2016) 14:186.
  • Vezzoli G, Dogliotti E, Terranegra A, Arcidiacono T, Macrina L, Tavecchia M, Pivari F, Mingione A, Brasacchio C, Nouvenne A, Meschi T, Cusi D, Spotti D, Montanari E, Soldati L. Dietary style and acid load in an Italian population of calcium kidney stone formers. Nutr Metab Cardiovasc Dis (2015) 25(6):588-93.
  • Soldati L, Kerkadi A, Amuna P, Terranegra A*. State of art and science advances on nutrition and nutrigenetics in nutrition-related non-communicable diseases in Middle East. J Transl Med (2015) 13(1):40
  • Soldati L, Bertoli S, Terranegra A, Brasacchio C, Mingione A, Dogliotti E, Raspini B, Leone A, Frau F, Vignati L, Spadafranca A, Vezzoli G, Cusi D, Battezzati A. Relevance of Mediterranean diet and glucose metabolism for nephrolithiasis in obese subjects. J Transl Med (2014) 12:34.
  • Nouvenne A, Ticinesi A, Guerra A, Folesani G, Allegri F, Pinelli S, Baroni P, Pedrazzoni M, Lippi G, Terranegra A, Dogliotti E, Soldati L, Borghi L, Meschi T. Influence of lean and fat mass on bone mineral density and on urinary stone risk factors in healthy women. J Transl Med (2013) 11:248.
  • Vezzoli G, Terranegra A, Aloia A, Arcidiacono T, Milanesi L, Mosca E, Mingione A, Spotti D, Cusi D, Hou J, Hendy Gn, Soldati L; on behalf of the GENIAL network (GeneticsEnvironment in Nephrolithiasis Italian Alliance). Decreased transcriptional activity of Calcium-sensing receptor gene promoter 1 is associated with calcium nephrolithiasis. J Clin Endocrinol Metab (2013) 98(9):3839-47.