Dr. Reem A. Hasnah is a postdoctoral fellow in the Translational Medicine Division at Sidra Medicine. She received her PhD in Biological and Biomedical Sciences from Hamad Bin Khalifa University, where she was trained under the guidance of Dr. Luis R. Saraiva. Her research integrates transcriptomics, spatial genomics, and functional biology to understand how specialized epithelial and sensory cells contribute to metabolism, immune regulation, and disease. Dr. Hasnah has extensive experience in RNA-seq, spatial transcriptomics, multi-omics integration, and disease modeling.

Dr. Hasnah’s research focuses on the use of transcriptomic and computational approaches to elucidate disease-associated molecular pathways and identify potential therapeutic opportunities. Her work aims to move beyond descriptive gene expression analyses toward a systems-level understanding of how genetic and environmental perturbations disrupt biological networks and drive disease phenotypes.

She integrates bulk and spatial transcriptomics with computational modeling to characterize disease signatures, dose–response relationships, and pathway-level perturbations across experimental and translational disease models. By combining differential expression analysis, pathway activity inference, and network-based approaches, her research seeks to identify core molecular mechanisms that are both disease-relevant and therapeutically actionable.

A central component of her research is the use of transcriptome-derived disease signatures for drug discovery and repurposing. She applies computational strategies such as pathway scoring, network analysis, and signature-reversal frameworks to predict compounds or interventions capable of restoring disease-altered molecular states. These predictions are designed to be experimentally testable in cellular and organismal systems.