Younes Mokrab, PhD

Principal Investigator - Associate level
Medical and Population Genomics Lab

ymokrab (@) sidra.org

Selected publications (†co-first, *corresponding):

  • Sastry KS, Naeem H, Mokrab Y, Chouchane AI. RNA-seq Reveals Dysregulation of Novel Melanocyte Genes upon Oxidative Stress: Implications in Vitiligo Pathogenesis. Oxid Med Cell Longev. 2019;2019:2841814. Published 2019 Dec 4. doi:10.1155/2019/2841814
  • Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS; Cancer Genome Atlas Research Network, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I.. The Immune Landscape of Cancer. Immunity. 2019;51(2):411-412. doi:10.1016/j.immuni.2019.08.004
  • Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium (Inc. Mokrab Y); Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes. Cell. 2018;173(7):1705-1715.e16. doi:10.1016/j.cell.2018.05.046
  • Hendrickx W, Simone I, Anjum S, Mokrab Y, Bertucci F, Finetti P, Curigliano G ,Seliger B, Pancione M, Maccalli C, Wang E, Miller L, Marincola F, Ceccarelli M, Bedognetti D. Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis. Oncoimmunology. 2017;6(2):e1253654. Published 2017 Feb 6. doi:10.1080/2162402X.2016.1253654
  • Randolph AL, Mokrab Y, Bennett AL, Sansom MS, Ramsey IS. Proton currents constrain structural models of voltage sensor activation. Elife. 2016;5:e18017. Published 2016 Aug 30. doi:10.7554/eLife.18017
  • Collier DA, Eastwood BJ, Malki K, Mokrab Y. Advances in the genetics of schizophrenia: toward a network and pathway view for drug discovery. Ann N Y Acad Sci. 2016;1366(1):61-75. doi:10.1111/nyas.13066
  • Franke B, Stein JL, Ripke S, ... Schizophrenia Working Group of the Psychiatric Genomics Consortium (Incl. Mokrab Y), et al. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nat Neurosci. 2016;19(3):420-431. doi:10.1038/nn.4228
  • Bulik-Sullivan BK, Loh PR, Finucane HK, ... Schizophrenia Working Group of the Psychiatric Genomics Consortium (Incl. Mokrab Y), et al. LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat Genet. 2015;47(3):291-295. doi:10.1038/ng.3211
  • Schizophrenia Working Group of the Psychiatric Genomics Consortium (Incl. Mokrab Y). Biological insights from 108 schizophrenia-associated genetic loci. Nature. 2014;511(7510):421-427. doi:10.1038/nature13595
  • Ramsey IS, Mokrab Y†, Carvacho I, Sands ZA, Sansom MSP, Clapham DE. An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1. Nat Struct Mol Biol. 2010;17(7):869-875. doi:10.1038/nsmb.1826