Ammira Akil PhD

BVMs, MSc, GC-LTHE1, EMBA, PhD
Principal Investigator – Assistant Level
Precision Medicine in Diabetes Laboratory

Email: aakil (@) sidra.org
Phone: +974 4003-7406 | +974 5059-7431
ORCID: http://orcid.org/0000-0001-5381-070X

Selected publications (†co-first, *corresponding):

  • *Akil, A. A.-S., et al. (2021). Diagnosis and treatment of type 1 diabetes at the dawn of the personalized medicine era." Journal of Translational Medicine 19(1): 137.
  • Rossi N, Aliyev E, Visconti A, Akil ASA, Syed N, Aamer W, Padmajeya SS, Falchi M, Fakhro KA. Ethnic-specific association of amylase gene copy number with adiposity traits in a large Middle Eastern biobank. NPJ Genom Med. 2021 Feb 9;6(1):8. doi: 10.1038/s41525-021-00170-3. PMID: 33563995; PMCID: PMC7873199.
  • Wong WKM, Joglekar MV, Saini V, Jiang G, Dong CX, Chaitarvornkit A, Maciag GJ, Gerace D, Farr RJ, Satoor SN, Sahu S, Sharangdhar T, Ahmed AS, Chew YV, Liuwantara D, Heng B, Lim CK, Hunter J, Januszewski AS, Sørensen AE, Akil ASA, Gamble JR, Loudovaris T, Kay TW, Thomas HE, O'Connell PJ, Guillemin GJ, Martin D, Simpson AM, Hawthorne WJ, Dalgaard LT, Ma RCW, Hardikar AA. Machine learning workflows identify a microRNA signature of insulin transcription in human tissues. iScience. 2021 Mar 31;24(4):102379. doi: 10.1016/j.isci.2021.102379. PMID: 33981968; PMCID: PMC8082091.
  • *Akil AA, Jerman LF, Yassin E, Padmajeya SS, Al-Kurbi A, Fakhro KA. Reading between the (Genetic) Lines: How Epigenetics is Unlocking Novel Therapies for Type 1 Diabetes. Cells. 2020 Nov 3;9(11):2403. doi: 10.3390/cells9112403. PMID: 33153010; PMCID: PMC7692667.
  • *Al-Shabeeb Akil, A.; Al-Maraghi, A.; Yassin, E.; Al-Malki, K.; FAKHRO, K. Latest Therapies for Type 1 Diabetes: Existing Setup and “Post-Insulin” Standpoints. Preprints 2020, 2020100578 (doi: 10.20944/preprints202010. 0578.v1).
  • *Akil, A. S., et al. (2020). Differentially Expressed Plasma miRNAs are closely associated with the presence of microvascular complications in Type 2 Diabetes: The 1000 Qatar-Omics Study Cohort." Diabetes 69(Supplement 1).
  • Amal Robay, Saleha Abbasi, Ammira Akil, Haitham El-Bardisi, Mohamed Arafa Ronald G. Crystal, and Khalid A. Fakhro. a systematic review on the genetics of male infertility in the era of next-generation sequencing. Arab J Urol. 2018 Feb 14;16(1):53-64. doi: 10.1016/j.aju.2017.12.003.
  • Ammira Al-Shabeeb Akil, Andy Ho, Carah A. Figueroa-Crisostomo, William D. Rawlinson, Maria E. Craig. MicroRNAs: A Link Between Type 1 Diabetes and the Environment? Pancreatic Islet Biology (pp 159-192), 2016; DOI 10.1007/978-3-319-45307-1_7. Springer International Publishing, Switzerland.
  • Ki Wook Kim,* Andy Ho,* Ammira Alshabeeb-Akil, Anandwardhan A. Hardikar, Thomas W.H.Kay, William D. Rawlinson, and Maria E. Craig. Coxsackievirus B5 Infection Induces Dysregulation of MicroRNAs Predicted to Target Known Type 1 Diabetes Risk Genes in Human Pancreatic Islets. Diabetes. 2016 Apr;65(4):996-1003. doi: 10.2337/db15-0956.
  • *Akil, A.S., E.A. Yassin, S.S. Padmajeya, L.A. Jerman, A. Fadda, W.H. Aamer, E.E. Aliyev, and K. Fakhro. One Novel 7.2 Kb Deletion In Exon 8 Of Insr Gene In Diabetic Qatari Female With Type A Insulin Resistance Syndrome: The 1000 Qatar-Omics Study Cohort. Diabetes Jun 2020, 69 (Supplement 1) 1748-P; DOI: 10.2337/db20-1748-P
  • Padmajeya, S.S., L. Jerman, A. Al-Kurbi, K. Fakhro, A.J. Jenkins, A. Hardikar, And A.S. Akil. The 1000 Qatar Omics Study: Development Of New Analytical Tools For Early Prediction And Treatment Of Diabetic Retinopathy In Qatar. Diabetes, 2019. 68(Supplement 1).