- Microbiology and Virology
Patrick Tang (MD, PhD) is the Division Chief of Pathology Sciences at Sidra Medicine. In this role, Dr. Tang is responsible for the development and implementation of new molecular and genomics-based tests for microbiology and infectious diseases, and other diagnostic disciplines in the clinical laboratory at Sidra. Dr. Tang will also lead a research program to advance microbial genomics and metagenomics to combat infectious diseases and outbreaks as well as better understand the role of microorganisms in human health and disease.
Prior to joining Sidra, Dr. Tang was a Clinician-Scientist leader at the British Columbia Centre for Disease Control (BCCDC) and a Clinical Associate Professor in the Department of Pathology and Laboratory Medicine at the University of British Columbia (UBC). His various roles included leading both the Tuberculosis (TB)/Mycobacteriology Laboratory, which provides TB diagnostic and reference services for the province of British Columbia, and the Molecular Microbiology and Genomics Program, which is responsible for the development and implementation of new molecular assays and technology platforms at the BCCDC Public Health Microbiology and Reference Laboratory.
Dr. Tang completed a combined MD/PhD at UBC where his research focused on the molecular pathogenesis of Listeria monocytogenes. During his pathology residency training at the University of Toronto, he played a multifaceted role during the 2003 SARS outbreak from performing the first laboratory tests for an unknown virus to managing infected patients to integrating large clinical datasets in order to better understand the virus. His experiences during the SARS outbreak led him to a post-doctoral fellowship at the University of California, San Francisco, where he helped to develop metagenomics-based methods for virus discovery.
Dr. Tang’s clinical and research interests are in the application of genomics and metagenomics to infectious diseases and public health as well as the development of novel molecular diagnostics. He is a pioneer in the use of whole-genome sequencing to understand outbreaks and the use of metagenomics to uncover new infectious agents. His research projects have included searching for novel infectious agents in chronic diseases and outbreaks, using genomics to reduce TB transmission, studying the microbiomes of people and animals, tracking the spread of avian influenza, and looking for better ways to monitor water pollution.
- Depletion of Human DNA in Spiked Clinical Specimens for Improvement
- Metagenomic investigation of plasma in individuals with ME/CFS
- A comprehensive method for amplicon-based and metagenomic characterization
- Declaring a tuberculosis outbreak over with genomic epidemiology
- Infection control in the new age of genomic epidemiology