Contrary to the dogma, not all Primary Immunodeficiency Disorders (PIDs) are rare and the prevalence of these conditions can be further increased in populations with high rates of consanguinity and large family sizes.
PIDs are a group of mostly monogenic diseases generally caused by loss- or gain-of-function mutations in over 300 known genes.
Many more gene defects underlying PIDs remain to be discovered. The clinical phenotypes associated with PIDs have enormously expanded over the last two decades. Novel types of PIDs cause a great variety of infectious, autoimmune, inflammatory, allergic or malignant diseases.
Currently, most PID patients from Qatar are studied and diagnosed abroad and the most severe cases are even managed abroad because the lack of local expertise and technology. This PID interest group aims to facilitate interaction between physicians and scientists to help build local expertise and capacity, taking advantage of a recently established international network of exceptional physicians and scientists who are experts in the field.
Our ambitious long-term goal is to improve patient care and to increase research capacity in Qatar, ultimately establishing Sidra as one of the world leaders in the field of PIDs.